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HES — Health Evolution Hub
Non-profit association · MadridI · VII
Monograph No. 01Madrid · MMXXVIHesalud.comRx · TDM · AI

The hub where healthcare imagines, learns and evolves.

HES is an incubator for clinical ideas: an association of healthcare professionals where projects, research and training grow out of real-world care. Scientific rigour, a vocation for change.

Explore the projectsAbout the association
What HES isII · VII

A hub, not an ivory tower.

We are clinicians who, faced with the absence of proper tools in daily practice, learned to build them. HES organizes that practice as an open, horizontal network with a continuous evolution mindset.

  1. 01

    Technology development

    Applied AI, clinical software and decision platforms, built from real care needs and validated in hospital settings.

  2. 02

    Clinical research

    Multicentre studies connecting evidence with practice: pharmacokinetics, patient-reported outcomes, real-world data.

  3. 03

    Training & outreach

    We share what we learn through courses, workshops and collaborations with scientific societies and public institutions.

Featured projectIII · VII
Sociedad Española de Farmacia Hospitalaria
1st PrizeVI SEFH Innovation Forum 20251 of 57 projects

KinetricKinetric

Precision dosing for drugs with a narrow therapeutic window.

A platform combining Bayesian pharmacokinetics and artificial intelligence to individualize doses in complex patients, embedded in the hospital clinical workflow.

Learn more about Kinetric
Kinetric · modelo PK/PDτ · λ
Recognition
1st prize among 57 projects · SEFH 2025
Maturity
TRL 5–6 · regulatory evaluation in progress
Framework
EU MDR · AI Act · SaMD
Media
Redacción Médica · Onda Cero · Cadena SER

PK

Bayesiano

IA

Clínica

TDM

Integrado

Fig. 1Precision dosing for drugs with a narrow therapeutic window.
Coming soonIV · VII

OPTIBIO-EII

Optimising biologic therapy in inflammatory bowel disease.

Multicentre study integrating pharmacokinetic monitoring with patient-reported outcomes (PROMs/PREMs) collected via NAVETA, with a network of partner hospitals.

Founding teamV · VII

Clinicians who build.

Three hospital pharmacists who share the belief that healthcare innovation happens when the clinical frontline has voice and hands.

Miguel Caselles Gil

PI & Coordinator

Miguel Caselles Gil

Hospital Pharmacist · H.U. Fuenlabrada (SERMAS)

Innovation & Processes Coordinator · Hospital Medical Directorate · PhD candidate · AEMPS Expert Network

Elena Gómez Bayona

Clinical research

Elena Gómez Bayona

Hospital Pharmacist · H.U. Ramón y Cajal · IRYCIS

Multicentre study coordination.

Irene Ruiz-Jarabo

Clinical validation

Irene Ruiz-Jarabo

Hospital Pharmacist · H.U. Getafe

Clinical implementation and integration into real practice.

In the mediaVI · VII

Clinical practice in the public conversation.

Kinetric has been covered by specialist healthcare media, general press and radio since the SEFH award in December 2025.

19Hits
16Outlets
2Radio
  • Redacción Médica
  • Diario Médico
  • Diariofarma
  • IM Médico
  • El Farmacéutico
  • El Global Farma
  • Cadena SER Madrid Sur
  • Onda Cero Madrid
  • iSanidad
  • El Debate
  • +6 more
See full coverageLatest: El Global Farma
CollaborateVII · VII

Many ways to take part.

HES is a growing network. If you share the vision, we can work together.